Dr Gayatri Satpathy


PGS is a genetic screening test which assess for chromosomal abnormalities in your embryos before it is implanted during an IVF cycle. This allows screening for the best embryos to be implanted thereby reducing the probability of an unhealthy fetus with certain congenital diseases.

In this technique a small biopsy is taken from an embryo which is then analyzed by comparative genomic hybridisation (aCGH) with chromosomal profiling of all 24 chromosomes so as to detect common genetic abnormalities like Down syndrome, Edwards syndrome and Patau syndrome etc. This way we can better select or deselect an embryo to transfer.

Who are offered this treatment?

  • Advanced maternal age ≥ 35 years
  • Couples with a history of recurrent and spontaneous miscarriages/ abortions.
  • Couples with multiple IVF or ICSI failures.
  • Couples having previous child with genetic abnormalities, thalassemia, colour blindness etc.
  • Strong family history of genetic diseases

The best advantage of PGS is that it reduces the time to pregnancy as your fertility specialist is able to select the best embryo before transfer which increases the likelihood of success post embryo transfer.



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